Sodium cyanoborohydride → HCID 19878414, compound

Participants

Reaction Steps

The compound (0.5 g) of Example 2 was dissolved in a mixture of methanol (5 ml) and acetic acid (5 ml) at 15° C. and to the stirred solution was added sodium cyanoborohydride (0.15 g). After one hour, the solution was concentrated in vacuo, water (20 ml) and chloroform (20 ml) were added and the organic phase separated and dried over anhy. sodium sulphate. Filtration and concentration of the filtrate in vacuo gave the desired produced (0.49 g).

Provenance & Evidence