HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 9911574, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Piperidine, 1-(2-chloroethyl)-, hydrochloride | HCID 74826 | — |
| Reactant | HCID 15129663 | HCID 15129663 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 9911574 | HCID 9911574 | — |
Reaction Steps
Eight g of the compound of Example 2 was combined with 16.3 g of potassium carbonate and 4.6 g of 1-(2-chloroethyl)piperidine hydrochloride in 75 ml of dimethylformamide under anhydrous conditions, and the process was carried out and the product isolated as described in Example 6 above. The 9.5 g of product from the chromatography was recrystallized from isopropanol to obtain 8.74 g of the desired product, m.p. 130°-133° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05147880 |
| Source dataset | uspto-grants-1992_09 |
| ORD ID | ord-cfd663bed0604d259beec68470b6136d |
| Source note | uspto-grants-1992_09 |