Carbon Dioxide → 2-Chloro-4,6-dimethoxy-1,3,5-triazine

Participants

Reaction Steps

To a stirred mixture of 45.0 grams of methanol and 5.0 grams of water was added 16.8 grams (0.2 mole) of sodium bicarbonate and 18.5 grams (0.1 mole) of cyanuric chloride. The addition caused the reaction mixture temperature to rise to 35° C. and the liberation of carbon dioxide gas. After the gas evolution slowed, the reaction mixture was heated to reflux where it stirred for 30 minutes. The reaction mixture was cooled, diluted with water, and the resultant solid was collected by filtration. The solid was washed repeatedly with water and dried to yield 13.0 grams of 2-chloro-4,6-dimethoxy-1,3,5-triazine, m.p. 74°-76° C. Recrystallization of the solid from heptane raised the melting point to 75°-76° C.

Provenance & Evidence