4-Nitrophenol → 4-Nitrophenyl 6-phenyl-2-(4,6-dimethoxypyrimidin-2-yloxy)benzoate

HRID 1885987Notes

Reaction equation

HRID 1885987 reaction equation
[C:1]1([C:7]2[C:12]([C:13]([OH:15])=[O:14])=[C:11]([O:16][C:17]3[N:22]=[C:21]([O:23][CH3:24])[CH:20]=[C:19]([O:25][CH3:26])[N:18]=3)[CH:10]=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[N+:27]([C:30]1[CH:35]=[CH:34][C:33](O)=[CH:32][CH:31]=1)([O-:29])=[O:28]>C(Cl)Cl>[C:1]1([C:7]2[C:12]([C:13]([O:15][C:33]3[CH:34]=[CH:35][C:30]([N+:27]([O-:29])=[O:28])=[CH:31][CH:32]=3)=[O:14])=[C:11]([O:16][C:17]3[N:18]=[C:19]([O:25][CH3:26])[CH:20]=[C:21]([O:23][CH3:24])[N:22]=3)[CH:10]=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 9804-NitrophenolHCID 148806476-Phenyl-2-(4,6-dimethoxypyrimidin-2-yloxy)benzoic acid

Product 1

HCID 198765944-Nitrophenyl 6-phenyl-2-(4,6-dimethoxypyrimidin-2-yloxy)benzoate

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

This compound is prepared in a manner analogous to that of Example 1, Step G, using equimolar amounts of 6-phenyl-2-(4,6-dimethoxypyrimidin-2-yloxy)benzoic acid, 4-nitrophenol, and dicyclohexylcarbiimide in methylene chloride, yielding 4-nitrophenyl 6-phenyl-2-(4,6-dimethoxypyrimidin-2-yloxy)benzoate.

Workup

  1. customThis compound is prepared in a manner analogous to that of Example 1, Step G

Sources & evidence

ORD record
ord-045a1f83fb7c482698fa5f82492f74ce
Source dataset
uspto-grants-1992_09
Patent number
US05149357

Reaction notes

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