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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1886003Generated: October 25, 2026

Trifluoroacetic acid → HCID 178481704, compound

https://huagongshe.com/reaction/1886003

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantTrifluoroacetyl fluorideHCID 67716—
ReactantN-MethylhydrazinecarbothioamideHCID 2723853—
ProductHCID 178481704HCID 178481704—

Reaction Steps

This exemplified compound may be readily synthesized by the reaction of methyl isocyanate with hydrazine to give 4-methyl-3-thiosemicarbazide followed by cyclocondensation with trifluoroacetic acid as described in U.S. Pat. No. 4,477,459. This compound may also be prepared by the reaction of 4-methyl-3-thiosemicarbazide with trifluoroacetylfluoride and heat (U.S. Pat. No. 3,780,052).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05149620
Source datasetuspto-grants-1992_09
ORD IDord-b98c545d21194b3c89942f661b4ae0d1
Source noteuspto-grants-1992_09