反应详情

温度

50 °C

To a stirred solution of 300 ml concentrated nitric acid, at room temperature, was added portionwise 73.2 g (0.48 mole) of 5-fluoro-2(3H)-benzoxazolone. The reaction mixture was warmed to 50° C., and was stirred for 4 hours. After cooling, the reaction mixture was poured onto ice. The precipitate which formed was collected, washed with water, and dried to give 72.8 g of the title compound as a brown powder: m.p. 207°-209° C.

1. temperatureAfter cooling
2. additionthe reaction mixture was poured onto ice
3. customThe precipitate which formed
4. customwas collected
5. washwashed with water
6. customdried