Allyl bromide → Allyl 3,5-dimethylphenyl ether

Participants

Reaction Steps

46.73 g (383 mmol) of 3,5-dimethylphenol (Compound No. 1) was dissolved in 100 ml of methyl ethyl ketone. To this solution, 55.6 g (460 mmol) of allyl bromide and 79.3 g (575 mmol) of anhydrous potassium carbonate were added. The thus obtained mixture was refluxed overnight under an argon atmosphere. The reaction mixture was then extracted with hexane. The extract was washed with a saturated aqueous solution of sodium chloride, dried over anhydrous magnesium sulfate, and concentrated, whereby 65.0 g of a crude 3,5-dimethyl-1-(2-propenyloxy)benzene (Compound No. 2) was obtained as a colorless oil.

Provenance & Evidence