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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1886237Generated: October 26, 2026

2-Fluoro-N-phenylacetamide → 4-Chloro-2-fluoroaniline

https://huagongshe.com/reaction/1886237

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-N-phenylacetamideHCID 9504—
Reactant4-Chloro-2-fluoroanilineHCID 93898—
Product4-Chloro-2-fluoroanilineHCID 93898—
Product4'-Chloro-2'-fluoroacetanilideHCID 853174—

Reaction Steps

U.S. Pat. No. 4,138,242 (Goddard, Feb. 6, 1979) relates to herbicidal compounds and their preparation from 4-chloro-2-fluoroaniline. The 4-chloro-2-fluoroaniline is prepared through the chlorination of 2-fluoroacetanilide to yield 4-chloro2-fluoroacetanilide and the subsequent formation of the desired aniline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05149875
Source datasetuspto-grants-1992_09
ORD IDord-bad640e6598f492f86717497c5a6435e
Source noteuspto-grants-1992_09