N-Methylbutylamine → 8-bromo-N-butyl-N-methyl-octanamide

HRID 1886245Notes

Reaction equation

HRID 1886245 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][C:9]([OH:11])=O.[CH3:12][NH:13][CH2:14][CH2:15][CH2:16][CH3:17]>>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][C:9]([N:13]([CH2:14][CH2:15][CH2:16][CH3:17])[CH3:12])=[O:11]

Participants

3

Reactant 2

HCID 8068N-MethylbutylamineHCID 5482758-Bromooctanoic acid

Product 1

HCID 226727438-bromo-N-butyl-N-methyl-octanamide

Procedure

Using the procedure of Step A of Example 3, 5 g of 8-bromo octanoic acid and 13 ml of N-methyl butylamine were reacted to obtain after chromatography on silica (eluant: methylene chloride-acetone 95-5), 6.14 g of the expected product.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-9984f98c425c475db7af9fad3a4f243a
Source dataset
uspto-grants-1992_09
Patent number
US05149696

Reaction notes

Loading…