L-Alanine → HCID 54033987, compound

Participants

Reaction Steps

Using the procedure described in Example 1, but replacing (S)-N-(S)-1-(ethoxycarbonyl)butyl]alanine by (S)-N-[(S)-1-carbamoylbutyl]alanine described in stage A of Example 3, and (3S)-3-carbamoyl-2-azobicyclo[2.2.2]-octane by (3S)-2-azabicyclo[2.2.2]octane-3-carboxylic acid n-octyl ester hydrochloride obtained in stage A (neutralized beforehand with triethylamine), the expected product is obtained from the product being purified by chromatography on silica gel (elution solvent: dichloromethane/ethanol, 95:5).

Provenance & Evidence