HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[1-(1H-imidazol-1-yl)-2-methylpropyl]-2-nitrobenzenamine → 4-[1-(1H-imidazol-1-yl)-2-methylpropyl]-1,2-benzenediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[1-(1H-imidazol-1-yl)-2-methylpropyl]-2-nitrobenzenamine | HCID 14518425 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-[1-(1H-imidazol-1-yl)-2-methylpropyl]-1,2-benzenediamine | HCID 14518426 | 100% |
Reaction Steps
A mixture of 31 parts of 4-[1-(1H-imidazol-1-yl)-2-methylpropyl]-2-nitrobenzenamine and 240 parts of ethanol was hydrogenated at 0.5.105Pa in a Parr apparatus and at room temperature with 30 parts of Raney nickel catalyst. After the calculated amount of hydrogen was taken up, the catalyst was filtered off over diatomaceous earth and the filtrate was evaporated, yielding 27.4 parts (100%) of 4-[1-(1H-imidazol-1-yl)-2-methylpropyl]-1,2-benzenediamine as a residue (interm. 117).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05151421 |
| Source dataset | uspto-grants-1992_09 |
| ORD ID | ord-d7dbd2c91e534097b3920ebfd2d6d9b7 |
| Source note | uspto-grants-1992_09 |