HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Nitrophenyl isothiocyanate → Ethyl 3-[[[(2-nitrophenyl)amino]thioxomethyl]amino]-1-pyrrolidinecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Nitrophenyl isothiocyanate | HCID 137690 | — |
| Reactant | Ethyl 3-aminopyrrolidine-1-carboxylate | HCID 13656208 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Ethyl 3-[[[(2-nitrophenyl)amino]thioxomethyl]amino]-1-pyrrolidinecarboxylate | HCID 15037311 | 100% |
Reaction Steps
A mixture of 15.8 parts of ethyl 3-amino-1-pyrrolidinecarboxylate, 18 parts of 1-isothiocyanato-2-nitrobenzene and 180 parts of tetrahydrofuran was stirred for 1 hour at room temperature. The reaction mixture was evaporated, yielding 34 parts (100%) of ethyl 3-[[[(2-nitrophenyl)-amino]thioxomethyl]amino]-1-pyrrolidinecarboxylate as a residue (int. 22).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05151424 |
| Source dataset | uspto-grants-1992_09 |
| ORD ID | ord-5594102111fe454ba2376e7050f7d760 |
| Source note | uspto-grants-1992_09 |