Phosphorus oxide (P4O10) → HCID 19876003, compound

HRID 1886446Notes

Reaction equation

HRID 1886446 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][CH2:10][CH2:11][C:12]([OH:14])=O)=[C:5]([N+:15]([O-:17])=[O:16])[CH:4]=1.O=P12OP3(OP(OP(O3)(O1)=O)(=O)O2)=O>C1(C)C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:8]=[C:7]2[C:6](=[C:5]([N+:15]([O-:17])=[O:16])[CH:4]=1)[NH:9][CH2:10][CH2:11][C:12]2=[O:14]

Participants

4

Reactant 2

HCID 14812Phosphorus oxide (P4O10)HCID 19876016HCID 19876016, compound

Product 1

HCID 19876003HCID 19876003, compoundYield 43.2%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Starting from 3-(4-methoxy-2-nitrophenylamino)propionic acid (50.0 g), phosphorus pentoxide (80.0 g) and toluene (350 ml), 2,3-dihydro-6-methoxy-8-nitro-4(1H)-quinolinone (yield 20.0 g) was obtained in a manner similar to Step 1 of Example 1.

Sources & evidence

ORD record
ord-85c75f837e2b4c9297f7cacfbb56cd18
Source dataset
uspto-grants-1992_09
Patent number
US05151431

Reaction notes

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