Phosphorus oxide (P4O10) → HCID 19876017, compound

HRID 1886447Notes

Reaction equation

HRID 1886447 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([NH:9][CH2:10][CH2:11][C:12]([OH:14])=O)=[C:4]([N+:15]([O-:17])=[O:16])[CH:3]=1.O=P12OP3(OP(OP(O3)(O1)=O)(=O)O2)=O>C1(C)C=CC=CC=1>[Cl:8][C:7]1[C:2]([Cl:1])=[CH:3][C:4]([N+:15]([O-:17])=[O:16])=[C:5]2[C:6]=1[C:12](=[O:14])[CH2:11][CH2:10][NH:9]2

Participants

4

Reactant 2

HCID 14812Phosphorus oxide (P4O10)HCID 19876010HCID 19876010, compound

Product 1

HCID 19876017HCID 19876017, compoundYield 26.7%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Starting from 3-(4,5-dichloro-2-nitrophenylamino)propionic acid (40.0 g), phosphorus pentoxide (70.0 g) and toluene (300 ml), 5,6-dichloro-2,3-dihydro-8-nitro-4(1H)-quinolinone (10.0 g) was obtained in a manner similar to Step 1 of Example 1.

Sources & evidence

ORD record
ord-631543997eaf4a0aae29f0ec34047bb1
Source dataset
uspto-grants-1992_09
Patent number
US05151431

Reaction notes

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