HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-3-nitrobenzyl alcohol → (3-Amino-2-methylphenyl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-3-nitrobenzyl alcohol | HCID 90289 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (3-Amino-2-methylphenyl)methanol | HCID 577175 | 87% |
Reaction Steps
A solution of 203 g of 2-methyl-3-nitrobenzyl alcohol in 1,000 ml of ethanol is hydrogenated in the presence of 5 g of 10% strength Pd/carbon at from 30° to 35° C. The catalyst is filtered off, the solution is evaporated down and the resulting solid is dried. 145 g of 3-amino-2-methylbenzyl alcohol of melting point 104° -108° C. are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05151441 |
| Source dataset | uspto-grants-1992_09 |
| ORD ID | ord-b95acf2c008c441989d7fec2b3e58a38 |
| Source note | uspto-grants-1992_09 |