HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1886497Generated: October 31, 2026
Triethylamine → (2S)-1-[(2S)-2-amino-3-phenylpropanoyl]pyrrolidine-2-carboxamide
https://huagongshe.com/reaction/1886497
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 70042899 | HCID 70042899 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | (2S)-1-[(2S)-2-amino-3-phenylpropanoyl]pyrrolidine-2-carboxamide | HCID 11557977 | — |
Reaction Steps
L-Phenylalanyl-L-prolinamide hydrobromide (480 mg) was dissolved in DMF (3 ml), to which was added triethylamine (0.29 ml) under cooling at -10° C. The mixture was stirred for 10 minutes under ice-cooling and the resultant precipitate was filtered off to give L-phenylalanyl-L-prolinamide in DMF solution, which was immediately used for the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05151497 |
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| Source dataset | uspto-grants-1992_09 |
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| ORD ID | ord-e82347b47a9644c68f67226208e716bd |
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| Source note | uspto-grants-1992_09 |
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