Potassium Hydroxide → Acridine, 2-methoxy-

HRID 1886528Notes

Reaction equation

HRID 1886528 reaction equation
[C:1]1([N:7]2[C:17]3[C:12](=[CH:13][C:14]([O:18][CH3:19])=[CH:15][CH:16]=3)[C:10](=O)C2=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-].[K+]>>[CH3:19][O:18][C:14]1[CH:15]=[CH:16][C:17]2[C:12](=[CH:10][C:2]3[C:1]([N:7]=2)=[CH:6][CH:5]=[CH:4][CH:3]=3)[CH:13]=1

Participants

3

Reactant 2

HCID 14797Potassium HydroxideHCID 19876382HCID 19876382, compound

Product 1

HCID 18690Acridine, 2-methoxy-

Procedure

The title compound can be prepared from N-phenyl-5-methoxy isatin of example 10 and 10% KOH by heating 2 hours on a steam bath. The solution is filtered, then acidified to pH 1 with conc. sulfuric acid. The product is collected by filtration.

Sources & evidence

ORD record
ord-5a9dd21543674d04a0ded31d195f4de8
Source dataset
uspto-grants-1992_09
Patent number
US05151518

Reaction notes

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