Potassium Hydroxide → 2-Methoxyacridine-9-carboxylic acid

HRID 1886530Notes

Reaction equation

HRID 1886530 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]2[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[C:12](=O)[C:10]2=[O:11])=[CH:5][CH:4]=1.[OH-:20].[K+]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]2[C:5](=[C:12]([C:10]([OH:20])=[O:11])[C:14]3[C:19]([N:9]=2)=[CH:18][CH:17]=[CH:16][CH:15]=3)[CH:4]=1

Participants

3

Reactant 2

HCID 14797Potassium HydroxideHCID 139250941-(4-Methoxyphenyl)indoline-2,3-dione

Product 1

HCID 219722722-Methoxyacridine-9-carboxylic acid

Procedure

The title compound can be prepared from N (4-methoxy phenyl) isatin of example 15 and 10% KOH by heating for 12 hours on a steam bath. The product is isolated as in example 25.

Sources & evidence

ORD record
ord-9064132c67a5432b807d9d61b177f9f4
Source dataset
uspto-grants-1992_09
Patent number
US05151518

Reaction notes

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