HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,4'-Dichlorobenzophenone → (E)-5,5-bis(4-chlorophenyl)-2,4-pentadienoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,4'-Dichlorobenzophenone | HCID 7034 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Triethyl 4-phosphonocrotonate, mixture of isomers | HCID 5365783 | — |
| Product | (E)-5,5-bis(4-chlorophenyl)-2,4-pentadienoic acid ethyl ester | HCID 14347256 | 28.1% |
Reaction Steps
By the method of Preparation 1, 4,4'-dichlorobenzophenone (5.00 g, 19.9 mmol) was hologated using triethyl 4-phosphonocrotonate (5.23 g, 20.9 mmol) and sodium hydride (0.528 g, 22 mmol) to give, after purification, 1.94 g (28% yield) of title product, mp 99-100° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05151545 |
| Source dataset | uspto-grants-1992_09 |
| ORD ID | ord-410908bc4aef4e039d767d523c529bd2 |
| Source note | uspto-grants-1992_09 |