HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 14534578, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 14534577 | HCID 14534577 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 14534578 | HCID 14534578 | 98% |
Reaction Steps
44 g of 8% strength sodium hydroxide solution are added to a solution of 15.3 g (73 millimoles) of 2-fluoro-3-isopropylbenzyl acetate in 100 ml of dioxane. After 5 hours at 50° C., the mixture is poured into 100 ml of water. 12 g (98%) of 2-fluoro-3-isopropylbenzyl alcohol are obtained by extraction with dichloromethane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05151548 |
| Source dataset | uspto-grants-1992_09 |
| ORD ID | ord-1c39f2704d294042aa79eeac6cf6eaae |
| Source note | uspto-grants-1992_09 |