Potassium Hydroxide → HCID 14534582, compound

Participants

Reaction Steps

26.4 g (99 millimoles) of 2-chloro-3-cyclohexylbenzyl acetate are added dropwise to a mixture of 150 ml of ethanol and 8.4 g (150 millimoles) of potassium hydroxide. After 6 hours at 50° C., the mixture is evaporated down under reduced pressure, water is added to the residue and the mixture is extracted with dichloromethane. After the organic phase has been worked up by a conventional method, it is subjected to fractional distillation under reduced pressure. 17.4 g (78%) of 2-chloro-3-cyclohexylbenzyl alcohol of boiling point 133°-135° C./0.5 mbar and nD20 =1.5593 are obtained.

Provenance & Evidence