Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 14534583 | HCID 14534583 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 14534584 | HCID 14534584 | 97.3% |
Reaction Steps
67 g of 8% strength aqueous sodium hydroxide solution are added to a solution of 25 g (0.11 mole) of 3-tert-butyl-2-fluorobenzyl acetate in 100 ml of dioxane and the mixture is stirred for 7 hours at 50° C., diluted with 100 ml of water and extracted three times with dichloromethane. Drying and evaporation give 19.5 g (97%) of 3-tert-butyl-2-fluorobenzyl alcohol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05151548 |
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| Source dataset | uspto-grants-1992_09 |
|---|
| ORD ID | ord-e8ecd4f8fe0b413eb8b2bdb087613ce3 |
|---|
| Source note | uspto-grants-1992_09 |
|---|
