3-(Trifluoromethyl)benzylamine → 2-(Methylamino)-N-(3-(trifluoromethyl)benzyl)-1,8-naphthyridine-3-carboxamide
Reaction equation
[CH3:1][NH:2][c:3]1[n:4][c:5]2[n:6][cH:7][cH:8][cH:9][c:10]2[cH:11][c:12]1[C:13](=[O:14])[OH:15].[F:16][C:17]([c:18]1[cH:19][c:20]([CH2:21][NH2:22])[cH:23][cH:24][cH:25]1)([F:26])[F:27]>>[CH3:1][NH:2][c:3]1[n:4][c:5]2[n:6][cH:7][cH:8][cH:9][c:10]2[cH:11][c:12]1[C:13](=[O:15])[NH:22][CH2:21][c:20]1[cH:19][c:18]([C:17]([F:16])([F:26])[F:27])[cH:25][cH:24][cH:23]1Participants
3
Sources & evidence
- ORD record
- ord-924b3dd155704cdaa92a9c591172f9e8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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