HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Fumaric Acid → 1-[3-(4-Fluorophenoxy)-1-azetidinylcarbonyl]-4-(phenylmethyl)piperazine fumarate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Fumaric Acid | HCID 444972 | — |
| Edukt | 1-[3-(4-Fluorophenoxy)-1-azetidinylcarbonyl]-4-(phenylmethyl)piperazine | HCID 15053405 | — |
| Lösungsmittel | Isopropanol | HCID 3776 | — |
| Produkt | 1-[3-(4-Fluorophenoxy)-1-azetidinylcarbonyl]-4-(phenylmethyl)piperazine fumarate | HCID 19799593 | 91,3% |
Reaktionsschritte
A 2.5 g portion of 1-[3-(4-fluorophenoxy)-1-azetidinylcarbonyl]-4-(phenylmethyl)piperazine was dissolved in isopropanol and treated with 0.8 g of fumaric acid dissolved in 2.5 ml of hot isopropanol. Upon cooling, the precipitate was collected by filtration, yielding 3 g (91.3%) of fine white crystals, m.p. 183°-184° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05151418 |
| Quelldatensatz | uspto-grants-1992_09 |
| ORD ID | ord-eb4470f878b043caa8b81cc8599cb950 |
| Quellennotiz | uspto-grants-1992_09 |