Ethyl Acetate → HCID 19432440, compound

Participants

Reaction Steps

To a solution of the dibenzofuran 23 (339 mg, 0.71 mmol) in anhydrous THF (7 mL) at 0° C. under a nitrogen atmosphere was added dropwise a 1M solution of tetrabutylammonium fluoride in THF (0.92 mL, 0.92 mmol). The reaction solution was stirred for 30 min., then saturated ammonium chloride was added. The mixture was then extracted with EtOAc and the organic solution was washed with brine. The organic solution was then dried with magnesium sulfate and then filtered and concentrated under vacuum. Flash chromatograhy of the residue (silica gel, 25% EtOAc in hexanes) provided 182 mg of 24 (70% yield) as a white solid.

Provenance & Evidence