HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phthalimide → N-(12-Bromododecyl)phthalimide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phthalimide | HCID 6809 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | Diisopropyl diazene-1,2-dicarboxylate | HCID 75555 | — |
| Reactant | 12-Bromo-1-dodecanol | HCID 137895 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-(12-Bromododecyl)phthalimide | HCID 10763182 | 93% |
Reaction Steps
Following general procedure A, 70.0 mmol (18.6 g) of 12-Bromododecan-1-ol, 77.0 mmol (20.2 g) of triphenylphosphine, 77.0 mmol (11.3 g) of phthalimide and 77.0 mmol (16.1 mL) of diisopropyl azo dicarboxylate were reacted in 350 mL of tetrahydrofuran for 2.5 h and the mixture was processed accordingly. The crude product was purified by column chromatography (cyclohexane/ethyl acetate 9:1). Yield 93%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08501199B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-b71fbd3aaf5f44f7b8931f466d2e2bce |
| Source note | uspto-grants-2013_08 |