反应详情

温度

165 °C

To polyphosphoric acid at 165° C. was added N-(5-nitro-2-oxo-1,2-dihydropyridin-3-yl)benzamide (300 mg, 1.16 mmol). The resulting mixture was then heated to 165° C. for 30 min. The solution was then poured into water. The resulting precipitate was collected by filtration, dissolved in diethyl ether, filtered through alumina and evaporated to afford 9 mg (3%) of the title compound.

1. filtrationThe resulting precipitate was collected by filtration
2. dissolutiondissolved in diethyl ether
3. filtrationfiltered through alumina
4. customevaporated