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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1887099Generated: November 3, 2026

Iodoethane → 4-Ethyl-6-(piperidin-4-yloxy)-isoquinoline

https://huagongshe.com/reaction/1887099

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodoethaneHCID 6340—
Reactant6-(Piperidin-4-yloxy)-4-(4,4,4-trifluoro-butyl)-isoquinolineHCID 57647069—
Product4-Ethyl-6-(piperidin-4-yloxy)-isoquinolineHCID 57646907—

Reaction Steps

The compound 266 was synthesized in a similar fashion as described for compound 90, using ethyl iodide. LCMS Method # 1, retention time 0.98 min, detected mass 257.31 [M+H]+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501736B2
Source datasetuspto-grants-2013_08
ORD IDord-e7342b8afa3349ec82c9f3b3e1a41fd2
Source noteuspto-grants-2013_08