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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1887117Generated: November 1, 2026

1-[(1-Methylpiperidin-3-yl)methyl]piperazine → 3-[4-(1-Methylpiperidin-3-ylmethyl)piperazin-1-yl]-6-(4-trifluoromethylphenyl)pyridazine

https://huagongshe.com/reaction/1887117

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[(1-Methylpiperidin-3-yl)methyl]piperazineHCID 2736940—
ReactantPyridazine, 3-chloro-6-[4-(trifluoromethyl)phenyl]-HCID 12449554—
Product3-[4-(1-Methylpiperidin-3-ylmethyl)piperazin-1-yl]-6-(4-trifluoromethylphenyl)pyridazineHCID 15951317—

Reaction Steps

The title compound was prepared by a similar procedure to that described in Example 1, starting from 3-chloro-6-(4-trifluoromethylphenyl)pyridazine and (1-methylpiperidin-3-ylmethyl)piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501739B2
Source datasetuspto-grants-2013_08
ORD IDord-8909280dd1914a40ae387257699ed863
Source noteuspto-grants-2013_08