1-Isopropylpiperazine → N-{4-[6-(4-Isopropylpiperazin-1-yl)pyridazin-3-yl]phenyl}acetamide

HRID 1887124Notes

Reaction equation

Cl[C:2]1[N:3]=[N:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([NH:14][C:15](=[O:17])[CH3:16])=[CH:10][CH:9]=2)=[CH:6][CH:7]=1.[CH:18]([N:21]1[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]1)([CH3:20])[CH3:19]>>[CH:18]([N:21]1[CH2:26][CH2:25][N:24]([C:2]2[N:3]=[N:4][C:5]([C:8]3[CH:13]=[CH:12][C:11]([NH:14][C:15](=[O:17])[CH3:16])=[CH:10][CH:9]=3)=[CH:6][CH:7]=2)[CH2:23][CH2:22]1)([CH3:20])[CH3:19]

Participants

Reactant 2

HCID 780131-Isopropylpiperazine

HCID 86637100HCID 86637100, compound

Product 1

HCID 15951318N-{4-[6-(4-Isopropylpiperazin-1-yl)pyridazin-3-yl]phenyl}acetamide

Procedure

The title compound was prepared by a similar procedure to that described in Example 1, starting from 3-chloro-6-(4-acetylaminophenyl)pyridazine and 1-isopropylpiperazine.

Sources & evidence

ORD record: ord-a663a9b164d448bca1ba0f1a05e72835
Source dataset: uspto-grants-2013_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08501739B2

Reaction notes

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