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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1887129Generated: October 30, 2026

1-(2-(Dimethylamino)ethyl)piperazine → Dimethyl-(2-{4-[5-(4-trifluoromethylphenyl)pyridin-2-yl]piperazin-1-yl}ethyl)amine

https://huagongshe.com/reaction/1887129

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-(Dimethylamino)ethyl)piperazineHCID 2736229—
Reactant2-Chloro-5-[4-(trifluoromethyl)phenyl]pyridineHCID 50852684—
ProductDimethyl-(2-{4-[5-(4-trifluoromethylphenyl)pyridin-2-yl]piperazin-1-yl}ethyl)amineHCID 15951384—

Reaction Steps

The title compound was prepared by a similar procedure to that described in Example 1, starting from 2-chloro-5-(4-trifluoromethylphenyl)pyridine and (2-dimethylaminoethyl)piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501739B2
Source datasetuspto-grants-2013_08
ORD IDord-0209439272444e9cb03e7c1e888a44e6
Source noteuspto-grants-2013_08