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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1887141Generated: October 31, 2026

Chloroacetone → 1-{4-[5-(4-Trifluoromethylphenyl)pyridin-2-yl]piperazin-1-yl}propan-2-one, hydrochloride

https://huagongshe.com/reaction/1887141

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroacetoneHCID 6571—
Reactant4-(5-(4-Trifluoromethylphenyl)pyridin-2-yl)piperazineHCID 67145002—
Product1-{4-[5-(4-Trifluoromethylphenyl)pyridin-2-yl]piperazin-1-yl}propan-2-one, hydrochlorideHCID 131730775—

Reaction Steps

The title compound was prepared by a similar procedure to that described in Example 55, starting from 4-(5-(4-trifluoromethylphenyl)pyridin-2-yl)piperazine and chloroacetone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501739B2
Source datasetuspto-grants-2013_08
ORD IDord-07b856e5516e451584b267a3890dbee1
Source noteuspto-grants-2013_08