N-bromobutanimide → HCID 68617641, compound

Participants

Reaction Steps

Following the procedure as described in Preparation 19, making variations only as required to use N-ethyl-3-methylthiophene-2-carboxamide in place of N-benzyl-3-methylfuran-2-carboxamide to react with N-bromosuccinimide, 5-bromo-N-ethyl-3-methylthiophene-2-carboxamide was obtained as a colorless oil in 92% yield: 1H NMR (300 MHz, CDCl3) δ 6.85 (s, 1H), 5.65 (br s, 1H), 3.48-3.38 (m, 2H), 2.45 (s, 3H), 1.22 (t, J=7.3 Hz, 3H); MS (ES+) m/z 248.1 (M+1), 250.1 (M+1).

Provenance & Evidence