4-Bromo-3-fluorobenzenesulfonyl chloride → 4-bromo-N-[5-(3,5-dimethylpiperazin-1-yl)-3-pyridinyl]-3-fluorobenzenesulfonamide

HRID 188732Notes

Reaction equation

HRID 188732 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([S:6]([NH:7][c:8]2[cH:9][cH:10][n:11][c:12]([Cl:13])[cH:14]2)(=[O:15])=[O:16])[cH:17][cH:18]1.[Br:34][c:35]1[c:36]([F:45])[cH:37][c:38]([S:41](=[O:42])(=[O:43])[Cl:44])[cH:39][cH:40]1.[CH3:19][CH:20]1[CH2:21][N:22]([c:27]2[cH:28][c:29]([NH2:33])[cH:30][n:31][cH:32]2)[CH2:23][CH:24]([CH3:26])[NH:25]1>>[CH3:19][CH:20]1[CH2:21][N:22]([c:27]2[cH:28][c:29]([NH:33][S:41]([c:38]3[cH:37][c:36]([F:45])[c:35]([Br:34])[cH:40][cH:39]3)(=[O:42])=[O:43])[cH:30][n:31][cH:32]2)[CH2:23][CH:24]([CH3:26])[NH:25]1

Participants

4

Reactant 3

HCID 27782184-Bromo-3-fluorobenzenesulfonyl chlorideHCID 589881394-Bromo-N-(2-chloro-4-pyridinyl)benzenesulfonamideHCID 686825945-(3,5-Dimethylpiperazin-1-yl)pyridin-3-amine

Product 1

HCID 686797564-bromo-N-[5-(3,5-dimethylpiperazin-1-yl)-3-pyridinyl]-3-fluorobenzenesulfonamide

Sources & evidence

ORD record
ord-11c61767b59749d695199593d3842b12
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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