HCID 68956174, compound → HCID 68951318, compound

Participants

Reaction Steps

A product obtained in Example 12 (0.045 g, 0.09 mmol) was hydrogenated in the present of Raney-Ni. The desired product was obtained following the synthetic procedure described in Example 1, 4, 7 or 10. The crude product was purified by silica chromatography to give the product (0.026 g, 70.7%). 1HNMR (CDCl3) δ: 1.03 (3H, t, CH3), 1.79 (2H, q, CH2), 2.64˜2.71 (3H, m, CH2), 3.19˜3.53 (5H, m, CH2 and N—CH), 3.82 (3H, s, Ar—OCH3), 3.88 (3H, s, Ar—OCH3), 3.93˜3.97 (2H, t, OCH2), 4.24 (1H, d, CH2), 5.54 (1H, brs, Ar—OH), 6.60 (1H, s, ArH), 6.85 (1H, s, ArH), 6.88 (1H, s, ArH).

Provenance & Evidence