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HRID 1887835作成日：2026年10月25日

6-(Methoxycarbonyl)pyridine-3-carboxylic acid → 5-[(7-Chloro-2-oxazol-2-yl-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-carbamoyl]-pyridine-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/1887835

反応式

関与物質

役割名称HCID仕込み量
反応物6-(Methoxycarbonyl)pyridine-3-carboxylic acidHCID 579631—
反応物3-aminomethyl-7-chloro-2-oxazol-2-yl-1-phenyl-1H-quinolin-4-oneHCID 71208332—
生成物5-[(7-Chloro-2-oxazol-2-yl-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-carbamoyl]-pyridine-2-carboxylic acid methyl esterHCID 71208328—

反応手順

5-[(7-Chloro-2-oxazol-2-yl-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-carbamoyl]-pyridine-2-carboxylic acid methyl ester was prepared starting from intermediate A and 6-(methoxycarbonyl)nicotinic acid. MS calcd. for C27H20ClN4O5 [(M+H)+] 515.1, obsd. 515.0.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08501732B2
出典データセットuspto-grants-2013_08
ORD IDord-d78e1cd4005c4f0ba2846c2ef53a5914
出典メモuspto-grants-2013_08