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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1887847Generated: October 26, 2026

p-(Methylsulphonyl)benzoic acid → 7-Chloro-3-[(4-methanesulfonyl-benzoylamino)-methyl]-4-oxo-1-phenyl-1,4-di-hydro-quinoline-2-carboxylic acid dimethylamide

https://huagongshe.com/reaction/1887847

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-(Methylsulphonyl)benzoic acidHCID 77670—
Reactant3-(aminomethyl)-7-chloro-N,N-dimethyl-4-oxo-1-phenyl-1,4-dihydroquinoline-2-carboxamideHCID 71208675—
Product7-Chloro-3-[(4-methanesulfonyl-benzoylamino)-methyl]-4-oxo-1-phenyl-1,4-di-hydro-quinoline-2-carboxylic acid dimethylamideHCID 71208292—

Reaction Steps

7-Chloro-3-[(4-methanesulfonyl-benzoylamino)-methyl]-4-oxo-1-phenyl-1,4-di-hydro-quinoline-2-carboxylic acid dimethylamide was prepared starting from intermediate C and 4-(methylsulfonyl)benzoic acid. MS calcd. for C27H24ClN3O5S [(M+H)+] 538.1, obsd. 538.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501732B2
Source datasetuspto-grants-2013_08
ORD IDord-3231b19b1c79445eb3c3a68d08bfd551
Source noteuspto-grants-2013_08