HRID1887850

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID18179616

1-Benzyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid

C13H11NO3

结构：CN(C)C(=O)c1c(CN)c(=O)c2ccc(Cl)cc2n1-c1ccccc1

HCID71208675

未命名化合物

PRODUCTS

生成物

结构：CN(C)C(=O)c1c(CNC(=O)c2ccn(Cc3ccccc3)c(=O)c2)c(=O)c2ccc(Cl)cc2n1-c1ccccc1

HCID71208711

未命名化合物

PROCEDURE

实验过程

3-{[(1-Benzyl-2-oxo-1,2-dihydro-pyridine-4-carbonyl)-amino]-methyl}-7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid dimethylamide was prepared starting from intermediate C and 1-benzyl-2-oxo-1,2-dihydro-pyridine-4-carboxylic acid. MS calcd. for C32H28ClN4O4 [(M+H)+] 567.2, obsd. 567.1.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6426e3d310434118aa19cd8f842e5ac1
来源数据集: uspto-grants-2013_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08501732B2
来源说明: uspto-grants-2013_08

反应 SMILES

[NH2:1][CH2:2][C:3]1[C:12](=[O:13])[C:11]2[C:6](=[CH:7][C:8]([Cl:14])=[CH:9][CH:10]=2)[N:5]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[C:4]=1[C:21]([N:23]([CH3:25])[CH3:24])=[O:22].[CH2:26]([N:33]1[CH:38]=[CH:37][C:36]([C:39](O)=[O:40])=[CH:35][C:34]1=[O:42])[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>>[CH3:24][N:23]([CH3:25])[C:21]([C:4]1[N:5]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[C:6]2[C:11]([C:12](=[O:13])[C:3]=1[CH2:2][NH:1][C:39]([C:36]1[CH:37]=[CH:38][N:33]([CH2:26][C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[C:34](=[O:42])[CH:35]=1)=[O:40])=[CH:10][CH:9]=[C:8]([Cl:14])[CH:7]=2)=[O:22]