Carzenide → HCID 71208765, compound

HRID 1887861Notes

Reaction equation

HRID 1887861 reaction equation
[NH2:1][CH2:2][C:3]1[C:12](=[O:13])[C:11]2[C:6](=[CH:7][C:8]([Cl:14])=[CH:9][CH:10]=2)[N:5]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:4]=1.[C:21]([C:24]1[CH:29]=[CH:28][C:27]([S:30]([NH2:33])(=[O:32])=[O:31])=[CH:26][CH:25]=1)(O)=[O:22]>>[Cl:14][C:8]1[CH:7]=[C:6]2[C:11]([C:12](=[O:13])[C:3]([CH2:2][NH:1][C:21](=[O:22])[C:24]3[CH:29]=[CH:28][C:27]([S:30](=[O:32])(=[O:31])[NH2:33])=[CH:26][CH:25]=3)=[CH:4][N:5]2[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 8739CarzenideHCID 712083983-(aminomethyl)-7-chloro-1-phenylquinolin-4(1H)-one

Product 1

HCID 71208765HCID 71208765, compound

Procedure

N-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-4-sulfamoyl-benzamide was prepared starting from intermediate D and 4-carboxybenzenesulfonamide. MS calcd. for C23H18ClN3O4S [(M+H)+] 467.9, obsd. 468.0.

Sources & evidence

ORD record
ord-5ad1872904674b9e8dde95826fe50dc4
Source dataset
uspto-grants-2013_08
Patent number
US08501732B2

Reaction notes

Loading…