Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1887862Generated: October 28, 2026

1-phenyl-1H-pyrazole-4-carboxylic acid → Phenyl-1H-pyrazole-4-carboxylic acid (7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-amide

https://huagongshe.com/reaction/1887862

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-phenyl-1H-pyrazole-4-carboxylic acidHCID 121026—
Reactant3-(aminomethyl)-7-chloro-1-phenylquinolin-4(1H)-oneHCID 71208398—
ProductPhenyl-1H-pyrazole-4-carboxylic acid (7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-amideHCID 71217343—

Reaction Steps

Phenyl-1H-pyrazole-4-carboxylic acid (7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-amide was prepared starting from intermediate D and 1-phenyl-1H-pyrazole-4-carboxylic acid. MS calcd. for C26H20ClN4O2 [(M+H)+] 455.1, obsd. 455.0.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501732B2
Source datasetuspto-grants-2013_08
ORD IDord-8dcfb9096cc04b41993e277f4ade444d
Source noteuspto-grants-2013_08