3-(aminomethyl)-7-chloro-1-phenylquinolin-4(1H)-one → HCID 71217345, compound

HRID 1887864Notes

Reaction equation

HRID 1887864 reaction equation
[NH2:1][CH2:2][C:3]1[C:12](=[O:13])[C:11]2[C:6](=[CH:7][C:8]([Cl:14])=[CH:9][CH:10]=2)[N:5]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:4]=1.[Cl:21][C:22]1[CH:38]=[CH:37][CH:36]=[CH:35][C:23]=1[CH2:24][N:25]1[CH:30]=[CH:29][C:28]([C:31](O)=[O:32])=[CH:27][C:26]1=[O:34]>>[Cl:14][C:8]1[CH:7]=[C:6]2[C:11]([C:12](=[O:13])[C:3]([CH2:2][NH:1][C:31]([C:28]3[CH:29]=[CH:30][N:25]([CH2:24][C:23]4[CH:35]=[CH:36][CH:37]=[CH:38][C:22]=4[Cl:21])[C:26](=[O:34])[CH:27]=3)=[O:32])=[CH:4][N:5]2[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 712083983-(aminomethyl)-7-chloro-1-phenylquinolin-4(1H)-oneHCID 71208471HCID 71208471, compound

Product 1

HCID 71217345HCID 71217345, compound

Procedure

1-(2-Chloro-benzyl)-2-oxo-1,2-dihydro-pyridine-4-carboxylic acid (7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-amide was prepared starting from intermediate D and 1-(2-chloro-benzyl)-2-oxo-1,2-dihydro-pyridine-4-carboxylic acid. MS calcd. for C29H22Cl2N3O3 [(M+H)+] 530.1, obsd. 530.0.

Sources & evidence

ORD record
ord-1a1c487f78fc43de961357f3b56f8225
Source dataset
uspto-grants-2013_08
Patent number
US08501732B2

Reaction notes

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