3-Methyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acid → HCID 71217348, compound

HRID 1887870Notes

Reaction equation

HRID 1887870 reaction equation
[NH2:1][CH2:2][C:3]1[C:12](=[O:13])[C:11]2[C:6](=[CH:7][C:8]([Cl:14])=[CH:9][CH:10]=2)[N:5]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:4]=1.[CH3:21][N:22]1[C:26]2=[N:27][CH:28]=[C:29]([C:31](O)=[O:32])[CH:30]=[C:25]2[N:24]=[CH:23]1>>[Cl:14][C:8]1[CH:7]=[C:6]2[C:11]([C:12](=[O:13])[C:3]([CH2:2][NH:1][C:31]([C:29]3[CH:30]=[C:25]4[N:24]=[CH:23][N:22]([CH3:21])[C:26]4=[N:27][CH:28]=3)=[O:32])=[CH:4][N:5]2[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 230002013-Methyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acidHCID 712083983-(aminomethyl)-7-chloro-1-phenylquinolin-4(1H)-one

Product 1

HCID 71217348HCID 71217348, compound

Procedure

3-Methyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acid (7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-amide was prepared starting from intermediate D and 3-Methyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acid. MS calcd. for C24H19ClN5O2 [(M+H)+] 444.1, obsd. 444.0.

Sources & evidence

ORD record
ord-ff608a22a4e643069645547be0ebd26d
Source dataset
uspto-grants-2013_08
Patent number
US08501732B2

Reaction notes

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