1-Benzyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid → HCID 71217350, compound

HRID 1887876Notes

Reaction equation

HRID 1887876 reaction equation
[NH2:1][CH2:2][C:3]1[C:12](=[O:13])[C:11]2[C:6](=[CH:7][C:8]([Cl:14])=[CH:9][CH:10]=2)[N:5]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:4]=1.[CH2:21]([N:28]1[C:33](=[O:34])[CH:32]=[CH:31][C:30]([C:35](O)=[O:36])=[CH:29]1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[Cl:14][C:8]1[CH:7]=[C:6]2[C:11]([C:12](=[O:13])[C:3]([CH2:2][NH:1][C:35]([C:30]3[CH:31]=[CH:32][C:33](=[O:34])[N:28]([CH2:21][C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=4)[CH:29]=3)=[O:36])=[CH:4][N:5]2[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 27642241-Benzyl-6-oxo-1,6-dihydropyridine-3-carboxylic acidHCID 712083983-(aminomethyl)-7-chloro-1-phenylquinolin-4(1H)-one

Product 1

HCID 71217350HCID 71217350, compound

Procedure

Benzyl-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid (7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-amide was prepared starting from intermediate D and 1-benzyl-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid. MS calcd. for C29H23ClN3O3 [(M+H)+] 496.1, obsd. 496.1.

Sources & evidence

ORD record
ord-1579e63d9b1941e5956e524ee017d9bc
Source dataset
uspto-grants-2013_08
Patent number
US08501732B2

Reaction notes

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