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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1887878Generated: October 28, 2026

1-Methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid → Methyl-2-oxo-1,2-dihydro-pyridine-4-carboxylic acid (7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-amide

https://huagongshe.com/reaction/1887878

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acidHCID 819923—
Reactant3-(aminomethyl)-7-chloro-1-phenylquinolin-4(1H)-oneHCID 71208398—
ProductMethyl-2-oxo-1,2-dihydro-pyridine-4-carboxylic acid (7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-amideHCID 71217352—

Reaction Steps

Methyl-2-oxo-1,2-dihydro-pyridine-4-carboxylic acid (7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-amide was prepared starting from intermediate D and 1-methyl-2-oxo-1,2-dihydro-pyridine-4-carboxylic acid. MS calcd. for C23H19ClN3O3 [(M+H)+] 420.1, obsd. 420.0.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501732B2
Source datasetuspto-grants-2013_08
ORD IDord-d218f7bd13014f98b7de75d3f0fd5ded
Source noteuspto-grants-2013_08