HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Morpholin-4-yl)pyrimidine-5-carboxylic acid → HCID 71217354, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Morpholin-4-yl)pyrimidine-5-carboxylic acid | HCID 3160979 | — |
| Reactant | 3-(aminomethyl)-7-chloro-1-phenylquinolin-4(1H)-one | HCID 71208398 | — |
| Product | HCID 71217354 | HCID 71217354 | — |
Reaction Steps
2-Morpholin-4-yl-pyrimidine-5-carboxylic acid (7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-amide was prepared starting from intermediate D and 2-morpholin-4-yl-pyrimidine-5-carboxylic acid. 1H NMR (400 MHz, DMSO-d6) δ ppm 8.67 (s, 2H) 8.55 (t, J=5.50 Hz, 1H) 8.21 (d, J=8.78 Hz, 1H) 7.90 (s, 1H) 7.56-7.67 (m, 3H) 7.49-7.55 (m, 2H) 7.39 (dd, J=8.66, 1.88 Hz, 1H) 6.84 (d, J=2.01 Hz, 1H) 4.29 (d, J=5.52 Hz, 2H) 3.67-3.76 (m, 3H) 1.52-1.61 (m, 2H) 1.39-1.48 (m, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08501732B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-d0dd5de081e042f3b05fb8dd482c5038 |
| Source note | uspto-grants-2013_08 |