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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1887887Generated: October 26, 2026

Diethanolamine → 6-[Bis-(2-hydroxy-ethyl)-amino]-N-(7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-yl-methyl)-nicotinamide

https://huagongshe.com/reaction/1887887

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethanolamineHCID 8113—
Reactant6-chloro-N-((7-chloro-4-oxo-1-phenyl-1,4-dihydroquinolin-3-yl)methyl)nicotinamideHCID 71487063—
Product6-[Bis-(2-hydroxy-ethyl)-amino]-N-(7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-yl-methyl)-nicotinamideHCID 71208373—

Reaction Steps

6-[Bis-(2-hydroxy-ethyl)-amino]-N-(7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-yl-methyl)-nicotinamide was prepared starting from intermediate E and diethanolamine. MS calcd. for C26H25ClN4O4 [(M+H)+] 493, obsd. 493.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501732B2
Source datasetuspto-grants-2013_08
ORD IDord-4a5005df540040dd9ebde3aabe66e6f9
Source noteuspto-grants-2013_08