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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1887896Generated: October 25, 2026

Ethanolamine → N-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-6-(2-hydroxy-ethyl-amino)-nicotinamide

https://huagongshe.com/reaction/1887896

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolamineHCID 700—
Reactant6-chloro-N-((7-chloro-4-oxo-1-phenyl-1,4-dihydroquinolin-3-yl)methyl)nicotinamideHCID 71487063—
ProductN-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-6-(2-hydroxy-ethyl-amino)-nicotinamideHCID 71208705—

Reaction Steps

N-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-6-(2-hydroxy-ethyl-amino)-nicotinamide was prepared starting from intermediate E and ethanolamine. MS calcd. for C24H21ClN4O3 [(M+H)+] 449.1, obsd. 449.0.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501732B2
Source datasetuspto-grants-2013_08
ORD IDord-6ba876bcdaf74b8c8638294dc4346876
Source noteuspto-grants-2013_08