Benzoyl chloride → HCID 71208262, compound

HRID 1887928Notes

Reaction equation

HRID 1887928 reaction equation
Cl.[CH3:2][O:3][C:4]([C:6]1[N:7]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:8]2[C:13]([C:14](=[O:18])[C:15]=1[CH2:16][NH2:17])=[CH:12][CH:11]=[C:10]([Cl:19])[CH:9]=2)=[O:5].[C:26](Cl)(=[O:33])[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>>[CH3:2][O:3][C:4]([C:6]1[N:7]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:8]2[C:13]([C:14](=[O:18])[C:15]=1[CH2:16][NH:17][C:26](=[O:33])[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)=[CH:12][CH:11]=[C:10]([Cl:19])[CH:9]=2)=[O:5]

Participants

3

Reactant 2

HCID 7412Benzoyl chlorideHCID 712085323-Aminomethyl-7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester hydrochloride

Product 1

HCID 71208262HCID 71208262, compound

Procedure

7-Chloro-3-[(benzoylamino)-methyl]-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester was prepared starting from intermediate I and benzoyl chloride. MS calcd. for C25H20ClN2O4 [(M+H)+] 447.1, obsd. 446.9.

Sources & evidence

ORD record
ord-b7c5be0963bd4eb89d0245d24a7d6344
Source dataset
uspto-grants-2013_08
Patent number
US08501732B2

Reaction notes

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