4-tert-Butylbenzoyl chloride → HCID 71208761, compound

HRID 1887939Notes

Reaction equation

HRID 1887939 reaction equation
[NH2:1][CH2:2][C:3]1[C:12](=[O:13])[C:11]2[C:6](=[CH:7][C:8]([O:14][CH3:15])=[CH:9][CH:10]=2)[N:5]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:4]=1[C:22]([O:24][CH3:25])=[O:23].[C:26]([C:30]1[CH:38]=[CH:37][C:33]([C:34](Cl)=[O:35])=[CH:32][CH:31]=1)([CH3:29])([CH3:28])[CH3:27]>>[CH3:25][O:24][C:22]([C:4]1[N:5]([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)[C:6]2[C:11]([C:12](=[O:13])[C:3]=1[CH2:2][NH:1][C:34](=[O:35])[C:33]1[CH:37]=[CH:38][C:30]([C:26]([CH3:28])([CH3:27])[CH3:29])=[CH:31][CH:32]=1)=[CH:10][CH:9]=[C:8]([O:14][CH3:15])[CH:7]=2)=[O:23]

Participants

3

Reactant 2

HCID 743724-tert-Butylbenzoyl chlorideHCID 71208438HCID 71208438, compound

Product 1

HCID 71208761HCID 71208761, compound

Procedure

3-[(4-tert-Butyl-benzoylamino)-methyl]-7-methoxy-4-oxo-1-phenyl-1,4-dihydro-quino-line-2-carboxylic acid methyl ester was prepared starting from intermediate K and 4-tert-butyl-benzoyl chloride. MS calcd. for C30H30N2O5 [(M+H)+] 499.2, obsd. 499.2.

Sources & evidence

ORD record
ord-6577cbb80af741b7aa0e2edad0ad6a4b
Source dataset
uspto-grants-2013_08
Patent number
US08501732B2

Reaction notes

Loading…