p-Anisoyl chloride → HCID 71208612, compound

HRID 1887940Notes

Reaction equation

HRID 1887940 reaction equation
[NH2:1][CH2:2][C:3]1[C:12](=[O:13])[C:11]2[C:6](=[CH:7][C:8]([O:14][CH3:15])=[CH:9][CH:10]=2)[N:5]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:4]=1[C:22]([O:24][CH3:25])=[O:23].[CH3:26][O:27][C:28]1[CH:36]=[CH:35][C:31]([C:32](Cl)=[O:33])=[CH:30][CH:29]=1>>[CH3:25][O:24][C:22]([C:4]1[N:5]([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)[C:6]2[C:11]([C:12](=[O:13])[C:3]=1[CH2:2][NH:1][C:32](=[O:33])[C:31]1[CH:35]=[CH:36][C:28]([O:27][CH3:26])=[CH:29][CH:30]=1)=[CH:10][CH:9]=[C:8]([O:14][CH3:15])[CH:7]=2)=[O:23]

Participants

3

Reactant 2

HCID 7477p-Anisoyl chlorideHCID 71208438HCID 71208438, compound

Product 1

HCID 71208612HCID 71208612, compound

Procedure

3-[(4-methoxy-benzoylamino)-methyl]-7-methoxy-4-oxo-1-phenyl-1,4-dihydro-quino-line-2-carboxylic acid methyl ester was prepared starting from intermediate K and 4-methoxybenzoyl chloride. MS calcd. for C27H24N2O6 [(M+H)+] 473.2, obsd. 473.2.

Sources & evidence

ORD record
ord-9ff2fbc44d2f48b492e63d81dcc54310
Source dataset
uspto-grants-2013_08
Patent number
US08501732B2

Reaction notes

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